Assay Detail
Functional
CHEMBL3602218
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Antimalarial activity against Plasmodium falciparum 3D7 assessed as inhibition of parasite growth
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From hybrid compounds to targeted drug delivery in antimalarial therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 7.47 | 8.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1783732 | — | — | 1 | 8.61 |
| CHEMBL3601442 | — | — | 1 | 8.05 |
| CHEMBL1277524 | — | — | 1 | 8.03 |
| CHEMBL3600962 | — | — | 1 | 7.69 |
| CHEMBL3601446 | — | — | 1 | 7.55 |
| CHEMBL3601445 | — | — | 1 | 7.45 |
| CHEMBL3286864 | — | — | 1 | 7.32 |
| CHEMBL3286857 | — | — | 1 | 7.24 |
| CHEMBL3601447 | — | — | 1 | 6.54 |
| CHEMBL3219153 | — | — | 1 | 6.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1783732 | — | IC50 | = | 2.48 | nM | 8.61 |
| CHEMBL3601442 | — | IC50 | = | 8.95 | nM | 8.05 |
| CHEMBL1277524 | — | IC50 | = | 9.3 | nM | 8.03 |
| CHEMBL3600962 | — | IC50 | = | 20.5 | nM | 7.69 |
| CHEMBL3601446 | — | IC50 | = | 28.4 | nM | 7.55 |
| CHEMBL3601445 | — | IC50 | = | 35.3 | nM | 7.45 |
| CHEMBL3286864 | — | IC50 | = | 48.2 | nM | 7.32 |
| CHEMBL3286857 | — | IC50 | = | 58.1 | nM | 7.24 |
| CHEMBL3601447 | — | IC50 | = | 287.6 | nM | 6.54 |
| CHEMBL3219153 | — | IC50 | = | 640.0 | nM | 6.19 |