Assay Detail
Functional
CHEMBL3602219
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Antimalarial activity against Plasmodium falciparum Dd2 assessed as inhibition of parasite growth
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From hybrid compounds to targeted drug delivery in antimalarial therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.48 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1254709 | DM-1157 | 1.0 | 1 | 8.80 |
| CHEMBL209953 | — | — | 1 | 8.30 |
| CHEMBL1096247 | — | — | 1 | 7.62 |
| CHEMBL3600962 | — | — | 1 | 7.59 |
| CHEMBL1774611 | — | — | 1 | 6.30 |
| CHEMBL3219153 | — | — | 1 | 6.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1254709 | DM-1157 | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL209953 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL1096247 | — | IC50 | = | 23.9 | nM | 7.62 |
| CHEMBL3600962 | — | IC50 | = | 25.7 | nM | 7.59 |
| CHEMBL1774611 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3219153 | — | IC50 | = | 580.0 | nM | 6.24 |