Assay Detail
Functional
CHEMBL3602220
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 assessed as inhibition of parasite growth
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From hybrid compounds to targeted drug delivery in antimalarial therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 7.65 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3601443 | — | — | 1 | 8.24 |
| CHEMBL3600963 | — | — | 1 | 7.97 |
| CHEMBL380230 | ARTEFLENE | 2.0 | 1 | 7.82 |
| CHEMBL476633 | — | — | 1 | 7.64 |
| CHEMBL3601444 | — | — | 1 | 7.64 |
| CHEMBL1096247 | — | — | 1 | 7.49 |
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 7.33 |
| CHEMBL3219153 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3601443 | — | IC50 | = | 5.7 | nM | 8.24 |
| CHEMBL3600963 | — | IC50 | = | 10.6 | nM | 7.97 |
| CHEMBL380230 | ARTEFLENE | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL476633 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL3601444 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL1096247 | — | IC50 | = | 32.6 | nM | 7.49 |
| CHEMBL269671 | ARTEMISININ | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL3219153 | — | IC50 | = | 80.0 | nM | 7.10 |