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Assay Detail

CHEMBL3602222

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Physicochemical
Inhibition of beta-hematin formation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

From hybrid compounds to targeted drug delivery in antimalarial therapy.
Oliveira R, Miranda D, Magalhães J, Capela R, Perry MJ, O'Neill PM, Moreira R, Lopes F.
Bioorg Med Chem (2015) 23 : 5120 -5130
PubMed 25913864 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.25 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1096247 1 8.70
CHEMBL1254709 DM-1157 1.0 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1096247 IC50 = 2.0 nM 8.70
CHEMBL1254709 DM-1157 IC50 = 1600.0 nM 5.80