Assay Detail
Functional
CHEMBL3602223
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Antimalarial activity against Plasmodium falciparum NF54 assessed as inhibition of parasite growth
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From hybrid compounds to targeted drug delivery in antimalarial therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| MIC | 2 | - | - |
| IC50 | 1 | 8.15 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1096247 | — | — | 1 | 8.15 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
| CHEMBL1289388 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1096247 | — | IC50 | = | 7.1 | nM | 8.15 |
| CHEMBL76 | CHLOROQUINE | MIC | = | 0.125 | ug.mL-1 | - |
| CHEMBL1289388 | — | MIC | = | 0.25 | ug.mL-1 | - |