Assay Detail
Functional
CHEMBL3602224
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Antimalarial activity against Plasmodium falciparum D10 assessed as inhibition of parasite growth
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
From hybrid compounds to targeted drug delivery in antimalarial therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.53 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3601448 | — | — | 1 | 8.40 |
| CHEMBL3601449 | — | — | 1 | 8.28 |
| CHEMBL3600962 | — | — | 1 | 7.67 |
| CHEMBL3600960 | — | — | 1 | 7.10 |
| CHEMBL1774611 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3601448 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL3601449 | — | IC50 | = | 5.2 | nM | 8.28 |
| CHEMBL3600962 | — | IC50 | = | 21.5 | nM | 7.67 |
| CHEMBL3600960 | — | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL1774611 | — | IC50 | = | 600.0 | nM | 6.22 |