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Assay Detail

CHEMBL3602229

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against Plasmodium falciparum F32
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

From hybrid compounds to targeted drug delivery in antimalarial therapy.
Oliveira R, Miranda D, Magalhães J, Capela R, Perry MJ, O'Neill PM, Moreira R, Lopes F.
Bioorg Med Chem (2015) 23 : 5120 -5130
PubMed 25913864 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.85 7.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3221874 1 7.89
CHEMBL3600963 1 7.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3221874 IC50 = 13.0 nM 7.89
CHEMBL3600963 IC50 = 15.7 nM 7.80