Assay Detail
Binding
CHEMBL3602688
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Inhibition of Influenza A/PR/8/34 (H1N1) core RNA-dependent RNA polymerase endonuclease activity using cap1 alfalfa mosaic virus RNA as substrate after 60 mins by liquid scintillation counting analysis in presence of [35S]-UTP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.37 | 6.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463590 | — | — | 1 | 6.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463590 | — | IC50 | = | 430.0 | nM | 6.37 |