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Assay Detail

CHEMBL3602689

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza A virus (A/PR8/34(H1N1)) infected in MDCK cells assessed as inhibition of viral replication after 24 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymerase.
Fudo S, Yamamoto N, Nukaga M, Odagiri T, Tashiro M, Neya S, Hoshino T.
Bioorg Med Chem (2015) 23 : 5466 -5475
PubMed 26252962 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.46 6.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL463590 1 6.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL463590 IC50 = 350.0 nM 6.46