Assay Detail
Functional
CHEMBL3603052
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Antimalarial activity against CQ-sensitive Plasmodium falciparum NF54 assessed as inhibition of parasite growth
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bayesian models trained with HTS data for predicting β-haematin inhibition and in vitro antimalarial activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53034 | — | — | 1 | 7.10 |
| CHEMBL3600462 | — | — | 1 | 7.09 |
| CHEMBL3600461 | — | — | 1 | - |
| CHEMBL1164544 | — | — | 1 | - |
| CHEMBL1650265 | — | — | 1 | - |
| CHEMBL3600460 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53034 | — | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL3600462 | — | IC50 | = | 82.0 | nM | 7.09 |
| CHEMBL3600461 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1164544 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL1650265 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL3600460 | — | IC50 | > | 10000.0 | nM | - |