Assay Detail
Functional
CHEMBL3603144
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Antiviral activity against HSV-1 7401H infected in African green monkey RC-37 cells after 2 to 3 days by plaque reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 1 |
| Cell Type | RC-37 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.24 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL431525 | BETUNOLIC ACID | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL431525 | BETUNOLIC ACID | IC50 | = | 5700.0 | nM | 5.24 |