Assay Detail
ADMET
CHEMBL3603343
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Binding affinity to human serum albumin with excitation at 295 nm after 30 mins by fluorescence spectrophotometric analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 5.23 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | 5.89 |
| CHEMBL3601027 | — | — | 1 | 5.72 |
| CHEMBL3601028 | — | — | 1 | 5.40 |
| CHEMBL3601026 | — | — | 1 | 4.72 |
| CHEMBL3601025 | — | — | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269277 | BETULINIC ACID | Kd | = | 1300.0 | nM | 5.89 |
| CHEMBL3601027 | — | Kd | = | 1900.0 | nM | 5.72 |
| CHEMBL3601028 | — | Kd | = | 4000.0 | nM | 5.40 |
| CHEMBL3601026 | — | Kd | = | 19000.0 | nM | 4.72 |
| CHEMBL3601025 | — | Kd | = | 37000.0 | nM | 4.43 |