Assay Detail
Binding
CHEMBL3606219
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant Trypanosoma brucei GAPDH assessed as oxidative phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate by spectrophotometric method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma brucei |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.00 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL256155 | — | — | 1 | 5.24 |
| CHEMBL3604082 | — | — | 1 | 5.00 |
| CHEMBL3604105 | — | — | 1 | 4.94 |
| CHEMBL3604098 | — | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL256155 | — | IC50 | = | 5730.0 | nM | 5.24 |
| CHEMBL3604082 | — | IC50 | = | 9920.0 | nM | 5.00 |
| CHEMBL3604105 | — | IC50 | = | 11600.0 | nM | 4.94 |
| CHEMBL3604098 | — | IC50 | = | 15600.0 | nM | 4.81 |