Assay Detail
Binding
CHEMBL3606853
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tight binding enantiomers of pre-clinical drug candidates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.24 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL514795 | — | — | 1 | 9.52 |
| CHEMBL3604359 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL514795 | — | Ki | = | 0.3 | nM | 9.52 |
| CHEMBL3604359 | — | Ki | = | 110.0 | nM | 6.96 |