Assay Detail
Functional
CHEMBL3607083
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Antiviral activity against Dengue virus infected in African green monkey Vero cells after 3 days by neutral red dye-based plaque reduction assay
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Dengue virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
2- and 3-Fluoro-3-deazaneplanocins, 2-fluoro-3-deazaaristeromycins, and 3-methyl-3-deazaneplanocin: Synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 5 | - | - |
| IC50 | 3 | 4.99 | 5.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3604361 | — | — | 1 | 5.15 |
| CHEMBL3604362 | — | — | 1 | 4.82 |
| CHEMBL3603846 | — | — | 1 | - |
| CHEMBL3604363 | — | — | 1 | - |
| CHEMBL3604364 | — | — | 1 | - |
| CHEMBL3604365 | — | — | 1 | - |
| CHEMBL3604366 | — | — | 1 | - |
| CHEMBL3604367 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3604361 | — | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL3604362 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL3603846 | — | IC50 | > | 228000.0 | nM | - |
| CHEMBL3604363 | — | Activity | - | — | - | |
| CHEMBL3604364 | — | Activity | - | — | - | |
| CHEMBL3604365 | — | Activity | - | — | - | |
| CHEMBL3604366 | — | Activity | - | — | - | |
| CHEMBL3604367 | — | Activity | - | — | - |