Assay Detail
Functional
CHEMBL3607085
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Antiviral activity against Influenza A virus H5N1 infected in MDCK cells after 3 days by neutral red dye-based plaque reduction assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
2- and 3-Fluoro-3-deazaneplanocins, 2-fluoro-3-deazaaristeromycins, and 3-methyl-3-deazaneplanocin: Synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.06 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3604361 | — | — | 1 | 6.00 |
| CHEMBL3603846 | — | — | 1 | 4.12 |
| CHEMBL3604362 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3604361 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3603846 | — | IC50 | = | 76000.0 | nM | 4.12 |
| CHEMBL3604362 | — | IC50 | = | 139000.0 | nM | - |