Assay Detail
Functional
CHEMBL3607182
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Measles virus infected in African green monkey CV1 cells after 3 days by neutral red dye-based plaque reduction assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Measles morbillivirus |
| Cell Type | CV-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
2- and 3-Fluoro-3-deazaneplanocins, 2-fluoro-3-deazaaristeromycins, and 3-methyl-3-deazaneplanocin: Synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.81 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31882 | DEZAGUANINE | 2.0 | 1 | 5.39 |
| CHEMBL3604363 | — | — | 1 | 5.07 |
| CHEMBL3604365 | — | — | 1 | 5.02 |
| CHEMBL3604367 | — | — | 1 | 4.52 |
| CHEMBL3604364 | — | — | 1 | 4.05 |
| CHEMBL3604366 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31882 | DEZAGUANINE | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL3604363 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL3604365 | — | IC50 | = | 9600.0 | nM | 5.02 |
| CHEMBL3604367 | — | IC50 | = | 30200.0 | nM | 4.52 |
| CHEMBL3604364 | — | IC50 | = | 89800.0 | nM | 4.05 |
| CHEMBL3604366 | — | IC50 | = | 162000.0 | nM | - |