Assay Detail
ADMET
CHEMBL3608161
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Antiproliferative activity against mouse BALB/3T3 cells after 72 hrs
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | BALB/3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid esters.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.77 | 6.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.51 |
| CHEMBL3605175 | — | — | 1 | 4.77 |
| CHEMBL1208572 | SALINOMYCIN | 2.0 | 1 | 4.56 |
| CHEMBL3605174 | — | — | 1 | 4.43 |
| CHEMBL3605173 | — | — | 1 | 4.40 |
| CHEMBL3605172 | — | — | 1 | 4.37 |
| CHEMBL3605176 | — | — | 1 | 4.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL3605175 | — | IC50 | = | 17010.0 | nM | 4.77 |
| CHEMBL1208572 | SALINOMYCIN | IC50 | = | 27760.0 | nM | 4.56 |
| CHEMBL3605174 | — | IC50 | = | 37010.0 | nM | 4.43 |
| CHEMBL3605173 | — | IC50 | = | 40090.0 | nM | 4.40 |
| CHEMBL3605172 | — | IC50 | = | 42490.0 | nM | 4.37 |
| CHEMBL3605176 | — | IC50 | = | 43370.0 | nM | 4.36 |