Assay Detail
Functional
CHEMBL3610693
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Antiviral activity against Influenza A virus H1N1 infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect by SRB assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-influenza activities of polyphenols from the medicinal mushroom Phellinus baumii.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.87 | 7.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 7.19 |
| CHEMBL487596 | INOSCAVIN A | — | 1 | 4.65 |
| CHEMBL218423 | PHELLIGRIDIN D | — | 1 | 4.61 |
| CHEMBL205945 | DAVALLIALACTONE | — | 1 | 4.37 |
| CHEMBL1224512 | HISPIDIN | — | 1 | 4.24 |
| CHEMBL1682260 | HYPHOLOMINE B | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222813 | ZANAMIVIR | IC50 | = | 64.7 | nM | 7.19 |
| CHEMBL487596 | INOSCAVIN A | IC50 | = | 22600.0 | nM | 4.65 |
| CHEMBL218423 | PHELLIGRIDIN D | IC50 | = | 24600.0 | nM | 4.61 |
| CHEMBL205945 | DAVALLIALACTONE | IC50 | = | 42800.0 | nM | 4.37 |
| CHEMBL1224512 | HISPIDIN | IC50 | = | 57900.0 | nM | 4.24 |
| CHEMBL1682260 | HYPHOLOMINE B | IC50 | = | 72800.0 | nM | 4.14 |