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Assay Detail

CHEMBL3614969

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-leishmanial activity against Leishmania major
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania major
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania major (CHEMBL612879)
Type ORGANISM
Organism Leishmania major

Publication

Chalcone scaffolds as anti-infective agents: structural and molecular target perspectives.
Mahapatra DK, Bharti SK, Asati V.
Eur J Med Chem (2015) 101 : 496 -524
PubMed 26188621 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.37 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL7747 4-HYDROXYCHALCONE 1 5.40
CHEMBL143265 1 5.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL7747 4-HYDROXYCHALCONE IC50 = 4000.0 nM 5.40
CHEMBL143265 IC50 = 4540.0 nM 5.34