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Assay Detail

CHEMBL3614979

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Trypanosoma cruzi trans-sialidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma cruzi
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Chalcone scaffolds as anti-infective agents: structural and molecular target perspectives.
Mahapatra DK, Bharti SK, Asati V.
Eur J Med Chem (2015) 101 : 496 -524
PubMed 26188621 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.83 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL199829 1 6.05
CHEMBL199442 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL199829 IC50 = 900.0 nM 6.05
CHEMBL199442 IC50 = 2500.0 nM 5.60