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Assay Detail

CHEMBL3615022

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Toxicity in human HepG2 cells assessed as cell viability
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model.
Roman BI, De Ryck T, Patronov A, Slavov SH, Vanhoecke BW, Katritzky AR, Bracke ME, Stevens CV.
Eur J Med Chem (2015) 101 : 627 -639
PubMed 26204510 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.00 5.00
Activity 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL61998 1 5.00
CHEMBL3613075 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL61998 EC50 = 10000.0 nM 5.00
CHEMBL3613075 Activity - -