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Assay Detail

CHEMBL3618798

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of NaV1.4 channel (unknown origin) expressed in Xenopus laevis oocytes by two-electrode oocyte voltage-clamp method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sodium channel protein type 4 subunit alpha (CHEMBL2072)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications.
de Lera Ruiz M, Kraus RL.
J Med Chem (2015) 58 : 7093 -7118
PubMed 25927480 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.21 10.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3617050 1 10.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3617050 IC50 = 0.062 nM 10.21