Assay Detail
Binding
CHEMBL3618917
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Inhibition of malt alpha-amylase
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.44 | 4.58 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL196 | ASCORBIC ACID | 4.0 | 1 | 4.58 |
| CHEMBL2115433 | — | — | 1 | 4.55 |
| CHEMBL220190 | ASCORBYL PALMITATE | -1.0 | 1 | 4.20 |
| CHEMBL45567 | — | — | 1 | - |
| CHEMBL45237 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL196 | ASCORBIC ACID | IC50 | = | 26500.0 | nM | 4.58 |
| CHEMBL2115433 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL220190 | ASCORBYL PALMITATE | IC50 | = | 62500.0 | nM | 4.20 |
| CHEMBL45567 | — | Inhibition | = | 99.0 | % | - |
| CHEMBL45237 | — | Inhibition | = | - | % | - |