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Assay Detail

CHEMBL3618924

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Binding
Inhibition of Escherichia coli MurC ligase after 15 mins by Malachite green assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors.
Al-Asri J, Fazekas E, Lehoczki G, Perdih A, Görick C, Melzig MF, Gyémánt G, Wolber G, Mortier J.
Bioorg Med Chem (2015) 23 : 6725 -6732
PubMed 26395057 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 3.46 3.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL599385 1 3.46
CHEMBL239103 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL599385 IC50 = 347000.0 nM 3.46
CHEMBL239103 IC50 = 531000.0 nM -