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Assay Detail

CHEMBL3618952

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human NaV1.2 channel by patch clamp electrophysiology assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sodium channel protein type 2 subunit alpha (CHEMBL4187)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Voltage-Gated Sodium Channels: Structure, Function, Pharmacology, and Clinical Indications.
de Lera Ruiz M, Kraus RL.
J Med Chem (2015) 58 : 7093 -7118
PubMed 25927480 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.62 6.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3617053 1 6.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3617053 IC50 = 240.0 nM 6.62