Assay Detail
Binding
CHEMBL3619925
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of fatty acid synthase (unknown origin) by scintillation proximity assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fatty Acid Synthase (FASN) Inhibitors as Potential Treatment for Cancer, Obesity, and Liver Related Disorders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.85 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3617746 | — | — | 1 | 7.52 |
| CHEMBL3617741 | — | — | 1 | 7.32 |
| CHEMBL3617742 | — | — | 1 | 7.25 |
| CHEMBL3617744 | — | — | 1 | 7.03 |
| CHEMBL3617743 | — | — | 1 | 6.75 |
| CHEMBL3617745 | — | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3617746 | — | IC50 | = | 30.2 | nM | 7.52 |
| CHEMBL3617741 | — | IC50 | = | 47.86 | nM | 7.32 |
| CHEMBL3617742 | — | IC50 | = | 56.23 | nM | 7.25 |
| CHEMBL3617744 | — | IC50 | = | 93.33 | nM | 7.03 |
| CHEMBL3617743 | — | IC50 | = | 177.83 | nM | 6.75 |
| CHEMBL3617745 | — | IC50 | = | 5888.44 | nM | 5.23 |