Assay Detail
Functional
CHEMBL3619930
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Antiproliferative activity against human PC3M cells expressing Luc-C6 in lipid reduced medium
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3M |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Fatty Acid Synthase (FASN) Inhibitors as Potential Treatment for Cancer, Obesity, and Liver Related Disorders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.08 | 7.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3617742 | — | — | 1 | 7.27 |
| CHEMBL3617744 | — | — | 1 | 6.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3617742 | — | IC50 | = | 53.7 | nM | 7.27 |
| CHEMBL3617744 | — | IC50 | = | 131.83 | nM | 6.88 |