Assay Detail
ADMET
CHEMBL3619937
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Cytotoxicity against mouse BALB/3T3 cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | BALB/3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-proliferative activity of Monensin and its tertiary amide derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.83 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.28 |
| CHEMBL3617681 | — | — | 1 | 5.11 |
| CHEMBL3617685 | — | — | 1 | 4.88 |
| CHEMBL256105 | MONENSIN | 4.0 | 1 | 4.68 |
| CHEMBL3617680 | — | — | 1 | 4.55 |
| CHEMBL3617683 | — | — | 1 | 4.48 |
| CHEMBL3617682 | — | — | 1 | 4.38 |
| CHEMBL3617684 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL3617681 | — | IC50 | = | 7730.0 | nM | 5.11 |
| CHEMBL3617685 | — | IC50 | = | 13090.0 | nM | 4.88 |
| CHEMBL256105 | MONENSIN | IC50 | = | 20890.0 | nM | 4.68 |
| CHEMBL3617680 | — | IC50 | = | 28110.0 | nM | 4.55 |
| CHEMBL3617683 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL3617682 | — | IC50 | = | 42010.0 | nM | 4.38 |
| CHEMBL3617684 | — | IC50 | = | 49640.0 | nM | 4.30 |