Assay Detail
Binding
CHEMBL3620073
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Inhibition of rat recombinant DDO using D-Asp
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.71 | 5.23 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1491941 | — | — | 2 | 5.23 |
| CHEMBL3617316 | — | — | 2 | 4.18 |
| CHEMBL7942 | MALONIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1491941 | — | Ki | = | 5890.0 | nM | 5.23 |
| CHEMBL3617316 | — | Ki | = | 65900.0 | nM | 4.18 |
| CHEMBL7942 | MALONIC ACID | Ki | = | 1562000.0 | nM | - |
| CHEMBL3617316 | — | Inhibition | - | % | - | |
| CHEMBL1491941 | — | Inhibition | - | % | - |