Assay Detail
Functional
CHEMBL3620198
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Cytotoxicity against human A549 cells by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic cardenolides from the latex of Calotropis procera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.60 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3617462 | — | — | 1 | 7.24 |
| CHEMBL3617460 | — | — | 1 | 7.19 |
| CHEMBL3617459 | — | — | 1 | 7.10 |
| CHEMBL500585 | USCHARIN | — | 1 | 6.98 |
| CHEMBL3617463 | — | — | 1 | 6.80 |
| CHEMBL3617461 | — | — | 1 | 6.46 |
| CHEMBL522203 | — | — | 1 | 6.26 |
| CHEMBL3617464 | — | — | 1 | 6.22 |
| CHEMBL3617465 | — | — | 1 | 5.99 |
| CHEMBL3617466 | — | — | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3617462 | — | IC50 | = | 58.0 | nM | 7.24 |
| CHEMBL3617460 | — | IC50 | = | 65.0 | nM | 7.19 |
| CHEMBL3617459 | — | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL500585 | USCHARIN | IC50 | = | 104.0 | nM | 6.98 |
| CHEMBL3617463 | — | IC50 | = | 157.0 | nM | 6.80 |
| CHEMBL3617461 | — | IC50 | = | 347.0 | nM | 6.46 |
| CHEMBL522203 | — | IC50 | = | 549.0 | nM | 6.26 |
| CHEMBL3617464 | — | IC50 | = | 604.0 | nM | 6.22 |
| CHEMBL3617465 | — | IC50 | = | 1016.0 | nM | 5.99 |
| CHEMBL3617466 | — | IC50 | = | 1693.0 | nM | 5.77 |