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Assay Detail

CHEMBL3624254

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [32P]diazirine-LPA from LPA receptor in mouse N1E-115 cells preincubated for 1 hr in dark followed by UV irradiation for 5 mins by scintillation counting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type N1E-115
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The status of the lysophosphatidic acid receptor type 1 (LPA1R)
Gonzalez-Gil I, Zian D, Vazquez-Villa H, Ortega-Gutierrez S, Lopez-Rodriguez ML
Medchemcomm (2015) 6 : 13 -23
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL117021 LYSOPHOSPHATIDIC ACID 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL117021 LYSOPHOSPHATIDIC ACID IC50 = 10.0 nM 8.00