Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3624414

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of glycogen phosphorylase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Computationally motivated synthesis and enzyme kinetic evaluation of N-(-d-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors
Begum J, Varga G, Docsa T, Gergely P, Hayes JM, Juhasz L, Somsak L
Medchemcomm (2015) 6 : 80 -89
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 6.63 6.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL490175 1 6.80
CHEMBL490001 1 6.46
CHEMBL423707 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL490175 Ki = 160.0 nM 6.80
CHEMBL490001 Ki = 350.0 nM 6.46
CHEMBL423707 Ki = 1700000.0 nM -