Assay Detail
Binding
CHEMBL3624602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human placental aromatase in presence of [1beta,2beta-3H] testosterone by Thompson and Siiteri method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent developments in steroidal and nonsteroidal aromatase inhibitors for the chemoprevention of estrogen-dependent breast cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.35 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL159073 | — | — | 1 | 7.40 |
| CHEMBL421149 | — | — | 1 | 7.37 |
| CHEMBL437731 | — | — | 1 | 7.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL159073 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL421149 | — | IC50 | = | 43.0 | nM | 7.37 |
| CHEMBL437731 | — | IC50 | = | 51.0 | nM | 7.29 |