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Assay Detail

CHEMBL3626077

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MDM2/p53 (unknown origin) interaction
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Tumour suppressor p53/oncoprotein Mdm2 (CHEMBL1907611)
Type PROTEIN-PROTEIN INTERACTION
Organism Homo sapiens

Publication

Rational design of proteinprotein interaction inhibitors
Rognan D
Medchemcomm (2015) 6 : 51 -60
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.05 9.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3621947 1 9.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3621947 Ki = 0.9 nM 9.05