Assay Detail
Binding
CHEMBL3626253
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of aspergillus niger alpha-galactosidase using 10 mM p-nitrophenyl-alpha-D-galactopyranoside as substrate
12
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Aspergillus niger |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Quaternary Indolizidine and Indolizidone Iminosugars as Potential Immunostimulating and Glycosidase Inhibitory Agents: Synthesis, Conformational Analysis, Biological Activity, and Molecular Docking Study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.86 | 7.05 |
| IC50 | 6 | 6.52 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3621528 | — | — | 2 | 7.05 |
| CHEMBL3621529 | — | — | 2 | 6.62 |
| CHEMBL3621532 | — | — | 2 | 6.48 |
| CHEMBL3621209 | — | — | 2 | 6.36 |
| CHEMBL3621533 | — | — | 2 | 4.85 |
| CHEMBL3621530 | — | — | 2 | 4.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3621528 | — | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL3621528 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL3621529 | — | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL3621532 | — | Ki | = | 330.0 | nM | 6.48 |
| CHEMBL3621532 | — | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL3621209 | — | Ki | = | 440.0 | nM | 6.36 |
| CHEMBL3621529 | — | Ki | = | 540.0 | nM | 6.27 |
| CHEMBL3621209 | — | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL3621533 | — | Ki | = | 14000.0 | nM | 4.85 |
| CHEMBL3621530 | — | Ki | = | 68000.0 | nM | 4.17 |
| CHEMBL3621533 | — | IC50 | = | 130000.0 | nM | - |
| CHEMBL3621530 | — | IC50 | = | 630000.0 | nM | - |