Assay Detail
Binding
CHEMBL3626595
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]lysergic acid diethylamide from human 5-HT6 receptor transfected in HEK293 cells after 60 mins by liquid scintillation spectrometry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic Potential of 5-HT6 Receptor Agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.05 | 8.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76237 | — | — | 1 | 8.64 |
| CHEMBL267615 | — | — | 1 | 7.80 |
| CHEMBL7318 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76237 | — | Ki | = | 2.3 | nM | 8.64 |
| CHEMBL267615 | — | Ki | = | 16.0 | nM | 7.80 |
| CHEMBL7318 | — | Ki | = | 20.0 | nM | 7.70 |