Assay Detail
Binding
CHEMBL3626906
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant HDAC11 using Ac-Leu-Gly-Lys (Ac)-AMC substrate incubated for 30 mins by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An azumamide C analogue without the zinc-binding functionality
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.55 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257972 | AZUMAMIDE C | — | 1 | 7.22 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 7.22 |
| CHEMBL3621348 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257972 | AZUMAMIDE C | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL98 | VORINOSTAT | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL3621348 | — | Ki | = | 6000.0 | nM | 5.22 |