Assay Detail
Functional
CHEMBL3630137
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of M-CSF/sRANKL-induced mouse BMDM differentiation into osteoclast after 72 hrs by TRAP staining-based microscopic analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | BMDM |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tumor necrosis factor ligand superfamily member 11 (CHEMBL3596084) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Identification of a molecular target of kurahyne, an apoptosis-inducing lipopeptide from marine cyanobacterial assemblages.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.11 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3628709 | — | — | 1 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3628709 | — | IC50 | = | 780.0 | nM | 6.11 |