Assay Detail
Binding
CHEMBL3630376
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-DPDPE from delta opioid receptor (unknown origin) transfected in HEK293 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.01 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL316446 | ENDOMORPHIN-1 | — | 1 | 5.22 |
| CHEMBL3629337 | — | — | 1 | 4.92 |
| CHEMBL3627737 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL316446 | ENDOMORPHIN-1 | Ki | = | 6080.0 | nM | 5.22 |
| CHEMBL3629337 | — | Ki | = | 12050.0 | nM | 4.92 |
| CHEMBL3627737 | — | Ki | = | 13280.0 | nM | 4.88 |