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Assay Detail

CHEMBL3632364

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to biotinylated-hairpin oligomer duplex A4GT4 DNA (unknown origin) by surface plasmon resonance method in presence of 0.1 M Na+ ion
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Target

Nucleic Acid (CHEMBL345)
Type NUCLEIC-ACID

Publication

Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair.
Paul A, Nanjunda R, Kumar A, Laughlin S, Nhili R, Depauw S, Deuser SS, Chai Y, Chaudhary AS, David-Cordonnier MH, Boykin DW, Wilson WD.
Bioorg Med Chem Lett (2015) 25 : 4927 -4932
PubMed 26051649 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 10.82 10.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3627920 1 10.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3627920 Kd = 0.015 nM 10.82