Assay Detail
Binding
CHEMBL3632436
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Competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase by multiplate reader method using p-nitrophenyl-alpha-D-glucopyranoside as substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Arylquinazolin-4(3H)-ones: A new class of α-glucosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.46 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137922 | — | — | 1 | 6.55 |
| CHEMBL3289115 | — | — | 1 | 6.37 |
| CHEMBL404271 | ACARBOSE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137922 | — | Ki | = | 283.0 | nM | 6.55 |
| CHEMBL3289115 | — | Ki | = | 430.0 | nM | 6.37 |
| CHEMBL404271 | ACARBOSE | Ki | = | 736000.0 | nM | - |