Assay Detail
Physicochemical
CHEMBL3635189
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Metal chelating activity assessed as inhibition of Fe2+-ferrozine complex formation after 10 mins
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Physicochemical |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.06 | 4.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL335206 | — | — | 1 | 4.07 |
| CHEMBL780 | PENTETIC ACID | 4.0 | 1 | 4.05 |
| CHEMBL14830 | ADENOSINE DIPHOSPHATE | 0.5 | 1 | - |
| CHEMBL153 | TROLOX | — | 1 | - |
| CHEMBL1261 | CITRIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL335206 | — | IC50 | = | 85000.0 | nM | 4.07 |
| CHEMBL780 | PENTETIC ACID | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL14830 | ADENOSINE DIPHOSPHATE | IC50 | = | 250000.0 | nM | - |
| CHEMBL153 | TROLOX | IC50 | = | 150000.0 | nM | - |
| CHEMBL1261 | CITRIC ACID | IC50 | = | 300000.0 | nM | - |