Assay Detail
Binding
CHEMBL3635489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-5-HT from human 5HT-1B receptor expressed in CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Applications of Fluorine in Medicinal Chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.83 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65367 | — | — | 1 | 7.96 |
| CHEMBL294732 | — | — | 1 | 7.82 |
| CHEMBL294547 | — | — | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65367 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL294732 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL294547 | — | IC50 | = | 19.0 | nM | 7.72 |