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Assay Detail

CHEMBL3636833

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human carbonic anhydrase 9
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Carbonic anhydrase 9 (CHEMBL3594)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII.
Ibrahim HS, Abou-Seri SM, Tanc M, Elaasser MM, Abdel-Aziz HA, Supuran CT.
Eur J Med Chem (2015) 103 : 583 -593
PubMed 26408817 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.96 8.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3633555 1 8.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3633555 Ki = 1.1 nM 8.96