Assay Detail
Functional
CHEMBL3637079
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Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
α-Halogenated oxaphosphinanes: Synthesis, unexpected reactions and evaluation as inhibitors of cancer cell proliferation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.39 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3633923 | — | — | 1 | 6.54 |
| CHEMBL3633922 | — | — | 1 | 6.45 |
| CHEMBL3633921 | — | — | 1 | 6.37 |
| CHEMBL3633920 | — | — | 1 | 6.35 |
| CHEMBL3633918 | — | — | 1 | 6.33 |
| CHEMBL3633919 | — | — | 1 | 6.32 |
| CHEMBL3633924 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3633923 | — | IC50 | = | 286.0 | nM | 6.54 |
| CHEMBL3633922 | — | IC50 | = | 359.0 | nM | 6.45 |
| CHEMBL3633921 | — | IC50 | = | 432.0 | nM | 6.37 |
| CHEMBL3633920 | — | IC50 | = | 445.0 | nM | 6.35 |
| CHEMBL3633918 | — | IC50 | = | 466.0 | nM | 6.33 |
| CHEMBL3633919 | — | IC50 | = | 478.0 | nM | 6.32 |
| CHEMBL3633924 | — | IC50 | - | — | - |