Assay Detail
Functional
CHEMBL3637080
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Antiproliferative activity against human MDA-MB-435 cells after 72 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-435 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
α-Halogenated oxaphosphinanes: Synthesis, unexpected reactions and evaluation as inhibitors of cancer cell proliferation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 9.27 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3633920 | — | — | 1 | 9.70 |
| CHEMBL3633919 | — | — | 1 | 9.52 |
| CHEMBL3633921 | — | — | 1 | 9.46 |
| CHEMBL3633923 | — | — | 1 | 9.28 |
| CHEMBL3633918 | — | — | 1 | 9.26 |
| CHEMBL3633924 | — | — | 1 | 8.84 |
| CHEMBL3633922 | — | — | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3633920 | — | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL3633919 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL3633921 | — | IC50 | = | 0.35 | nM | 9.46 |
| CHEMBL3633923 | — | IC50 | = | 0.52 | nM | 9.28 |
| CHEMBL3633918 | — | IC50 | = | 0.55 | nM | 9.26 |
| CHEMBL3633924 | — | IC50 | = | 1.45 | nM | 8.84 |
| CHEMBL3633922 | — | IC50 | = | 1.6 | nM | 8.80 |