Assay Detail
Functional
CHEMBL3637089
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Antimigratory activity in human MDA-MB-435 cells after 24 hrs by fibronectin-coated boyden chamber assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-435 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
α-Halogenated oxaphosphinanes: Synthesis, unexpected reactions and evaluation as inhibitors of cancer cell proliferation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.51 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3633919 | — | — | 1 | 7.55 |
| CHEMBL3633921 | — | — | 1 | 7.55 |
| CHEMBL3633924 | — | — | 1 | 7.55 |
| CHEMBL3633925 | — | — | 1 | 7.55 |
| CHEMBL3633918 | — | — | 1 | 7.54 |
| CHEMBL3633922 | — | — | 1 | 7.44 |
| CHEMBL3633920 | — | — | 1 | 7.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3633919 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL3633921 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL3633924 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL3633925 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL3633918 | — | Ki | = | 29.0 | nM | 7.54 |
| CHEMBL3633922 | — | Ki | = | 36.0 | nM | 7.44 |
| CHEMBL3633920 | — | Ki | = | 39.0 | nM | 7.41 |