Assay Detail
Binding
CHEMBL3705046
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding Assay: Binding assay using alpha 7 nAChR.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL2492) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
3-substituted-2-(arlyalkyl)-1-azabicycloalkanes and methods of use thereof
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.68 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2151571 | — | — | 1 | 8.30 |
| CHEMBL3640294 | — | — | 1 | 8.15 |
| CHEMBL3640295 | — | — | 1 | 8.05 |
| CHEMBL372419 | — | — | 1 | 7.40 |
| CHEMBL3640293 | — | — | 1 | 7.28 |
| CHEMBL193996 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2151571 | — | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL3640294 | — | Ki | = | 7.0 | nM | 8.15 |
| CHEMBL3640295 | — | Ki | = | 9.0 | nM | 8.05 |
| CHEMBL372419 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL3640293 | — | Ki | = | 53.0 | nM | 7.28 |
| CHEMBL193996 | — | Ki | = | 120.0 | nM | 6.92 |