Assay Detail
Binding
CHEMBL3705296
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Binding Assay: Binding affinity of protein kinase C (PKC).
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bryostatin analogues, synthetic methods and uses
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.37 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3674584 | — | — | 1 | 8.80 |
| CHEMBL3674583 | — | — | 1 | 8.64 |
| CHEMBL3674585 | — | — | 1 | 8.51 |
| CHEMBL3674586 | — | — | 1 | 8.42 |
| CHEMBL3674587 | — | — | 1 | 8.34 |
| CHEMBL3674588 | — | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3674584 | — | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL3674583 | — | IC50 | = | 2.3 | nM | 8.64 |
| CHEMBL3674585 | — | IC50 | = | 3.1 | nM | 8.51 |
| CHEMBL3674586 | — | IC50 | = | 3.8 | nM | 8.42 |
| CHEMBL3674587 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL3674588 | — | IC50 | = | 30.0 | nM | 7.52 |